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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f4172a7dccc154956f8895c76d92c5f43d2173961c86447167e8ee73db2eab' 
  AND token = 'mMBQJB0T/e+jSVVjAiy3UupY9a+iJzdR9uOEPUADoUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}