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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa25aab533e7e6a5a3f2088f700b4c60abe8929822e2cdba1b394b295b7b7ce3' 
  AND token = '3lqYuEbWOYAfAKY74XcTenEoBVPg5s2nA1BbyFIFFy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}