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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59318ccb5bcb569c8e2ab6c3eab721ce0724377b14ee1ebd96bd012684cd774c' 
  AND token = 'CN+3JBiUxpApwUUw6G/kpfjGlJHbeAcAf2iK68dpJLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}