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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303ff5f39633020daad7893dc21d8f950c079c600b3769834f54881b826d92a4' 
  AND token = 'C+kJRZbcks5bBmsO73/+OkjBNV2QN8fr7m+YKsLDcnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}