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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eb053280aec58417caa4d3effaf489c0c64855e6dfd03ee9f8082f9282c70d4' 
  AND token = 'jjXWCutun8ziB6eaic3hy25Bc/Eq2mEm+aXB6kO6UZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}