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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1eba1d8d575400d11cec134e18e897567189d9a06a68f64db2d1b026b28860' 
  AND token = 'P/iu9Lc6iY//AG4n2Ocl9IbOU4EL6prYz4/0VEyn024=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}