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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bf9bf9255359954d8831c653377e4972ed300548b2687127ae65e245b4b6340' 
  AND token = 'nLwCdak/q6ws1h9bFawsJ2V3y3WMmF8p/aDSLLm2vEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}