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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4cf7a1d80e26e3993b14389c95d0b93f3ed001d52488f0b6a012e919983f3e' 
  AND token = 'o+V+mYOIfVCLNNSN7YKnp1eyBIYxNe8su4qtGDXhy08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}