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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8901168894122f87f0e7bdebdb86e1e05f22e141d3285c8a4fe4d85a664884c' 
  AND token = '/60pY8YkXcIat69a98vwd78uEnixZwngpwcNi0xro7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}