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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35339de8bb7633768537c5eae2e3b6c2b8876a3ad5d5a89aa9e85a05f5015504' 
  AND token = 'fMHrI08qQL0ndJ2YNrgwkN1fwwFj1nw9WPzyUVxPgUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}