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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c1d845434089becbe67cede2884aefee24ec65c73872a80b1e5773bee9fb67' 
  AND token = '0nJt4LKtCr4nTvsKGRwiiaXrV5agF8nYsbUBDc0ga1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}