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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad478e12135513f62053a8d24475b7e9d41045085cb4276e4c9cc2d6b754fd52' 
  AND token = 'NUEjHDt2Mk0risPE9WvEOyuLTRfFx9dmEDaVHwUlBDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}