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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eef78f9f923938c1a8d9ceed8897bf1abebcc31733e2f6954fc219ee09c87125' 
  AND token = 'Cn9K/vvoMYnXtHVy9POnOW/UJNqyrtAupHfp0VaiN+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}