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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1973aa41fefa3cdec025255ba18b87985b0a8e4b4e2949171d205db4323d4d24' 
  AND token = '6E2Z6iVRT7GPqVyq7tOA4iRWQHJ/amHDe4Y66rPTbkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}