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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e296601ce7b36f54dd601df3e44b06f730989b6606ff2f066bae423f14998d9' 
  AND token = '1VdQL5Xo3UGtXn00gBWqrlNcOUYId8chff/AB80HSdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}