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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1347861091729faa9e18a1297996163deffbb283bec974c8c0297fc7f5bcf9a' 
  AND token = 'UTNR8e6ta99HXFeB4NAbHeJd/Ru5amGxsaEU4yb52/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}