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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6e73f3249aff92bf79c20336590072240a0afd3a6c117f4f701d093d7eb99f' 
  AND token = 'FSKDIL5iZaTRC5jo1/ueJM5PKe9K3jhKTbrdr6s7AG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}