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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420250e39f0760b1417970bf303eade18175f74cbd745d0e4cc5a273d57649b4' 
  AND token = 'O6PsuZjMCpAYrbMz93z6ZIOyU06BGyM08mVkqqbylXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}