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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7431da79def754c50df5a23b675d3b4a42dc8ec011e6d348cd1c6014fe33b7a9' 
  AND token = '+6WvO1fSqA2HkUukd7ArRiy8ZaX0pwtUDUFM5EZ47Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}