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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68f4a7914a377003b99b1337c575a299f327f72158ab25413ec1a11722510bce' 
  AND token = 'AMw+zyxQoV7VmA9lkL+XPxH/+/hGSGGGoMzsUt0w58Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}