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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fab503f76c514979d6b51be69702912dd72aff278ab1a873ae7166d3206b277' 
  AND token = 'oS5GEpa04/rImH7s/FxkewmZcCiBTPHlCaxBLivlZ8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}