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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '175392f1bb9cb66bc9914a95e43d432bdd5fbe168889df74586fa9846494b89d' 
  AND token = '/7UZS4fgGaiL5+cZQy+HjaFKdfhe9MsW956GPb0NXPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}