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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3770c5e1ac091d9889701e057cddc913436845b4290a6cac97239cee3c420613' 
  AND token = 'KiYvlbVG7zAXNBUuXo+qYPPtcvfaAh2A3QFqnJQmdkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}