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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1dd924b81b8b736ad4a7a4dc20a014b13208012dc2b7ed0f86a0197478d7d8' 
  AND token = 'dYlp9nvjO9K8kYzx/6Z5La9aLX0Gt4NdjVP42UBOqpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}