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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da96e0a07c50d957c53c3888c290b61bfe09ca1083a52209dbf15f9db941332' 
  AND token = 'LIW3FB8WVNR6VGrTHomAgv4fTmUD9fpnQOVpOW2Lg0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}