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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cbb049da6eee2a91cab4502fa0d0fd19053463f540f2528900d5d8ce7f6f601' 
  AND token = 'GL7bXXPRShnHzYB+BBw86EvR208NP6lAgN2gy4wgVxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}