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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0d9f63a1934a48cb5befbf562cb031f0c269209d3af44e62f374178a9e7932' 
  AND token = 'lKEuSsmzPlXJgfavN6YdmfhDAQWd0gPVfyp49qp0YNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}