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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583223a1669905902e62e54e79a5a117dc2ad13a58a412a3c31f6a4044ea9fe6' 
  AND token = '5ikeWJh+sfuN8FvzAT9CKMDKIMPRC4gXDC8ZPQXKLcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}