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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db52ea2f0cc148e9c01e4b59a0f232e77ba0e45e92a8de487f416232c592800c' 
  AND token = '+QgHHgv1e9PjN2SyNtbQEn32W04l45QJlpAEbbiDgPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}