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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d43e6760fe1d2e43888ee7acbe4ca5a49047254b839a5893d5316b4ea96e78' 
  AND token = 'Ly43nqMClEUUCSsrVuBkGq1Vcx5XHrzyo6Se1Dg3hwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}