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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28172c1c06ca658b55edfc53d76e84f9c5c7b5834270dbcc9b9d5b1178005847' 
  AND token = 'sE7+jBvnbPj9UqsexFMw/CJBTeoZg03454EHty+XkYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}