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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87e2e954dc61d0b7b744b8330c8bc6d21be92dc03e46be4a5259c5376ad31241' 
  AND token = 'SEPKSHQON8sqoS0Jae3F1STrtMq7GIbp02THAJPyeGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}