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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e048c374809a44ea54faca9550b9ab23f1e79c4673cb5492992d8e8c7478f5c1' 
  AND token = '2maekrxVtfs6lfZbDetCIO9rovNPjsG/9y98MVk0nvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}