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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17145e4b966815be8b419b3759a6955ddccb2a2830fc74ecaf6939383f38a04b' 
  AND token = 'KZOqN9GR+mUmumblbu0dyORLlimMT/W2Ijm7GeeB2ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}