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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '574158e89e82b4a58e0c91527dacacd91bcbbef594543a45fabc42bde48b7649' 
  AND token = 'REeH/TrPCb0GBtKoaWCCwEaR34y8GBuvdc+QLfZv5sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}