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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3802f9f29325f032f2908f3dbc6d26d476251f49fbb112deec0793ac5d462180' 
  AND token = 'bUcKkiov9NlvXjVFdeT35slAs3zckRdsIsRUG64nHwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}