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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88044401efd5478bae7ca1d968a20fc74fd4cdc11528bf0d2e0c3847ff3007bd' 
  AND token = 'x81dBTRzL01EH7Q+ZE/wmyzXikyOU2ZY6Ol0tdfppW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}