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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ee846c80680fa3e5a75a930bd029a308bd47fa6dc2f2562ad4bb485a2755ea' 
  AND token = 'sscbKXpK5Z1484QyOiYCB4mvMuu3vXLelt+vv5g7zQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}