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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b0eff1eceaf88e910048c61ea15035aa3069ced5dd9f272fde4e6b6f9c10d8' 
  AND token = 'PnlZzlZ0nLbbRfZXlSdjaRLGlFq8Ho5eNgE1EgsJF50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}