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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc7d94469818ce93553d6d221ebeb28bb3b510404ddb173f331d827e71f2f8c2' 
  AND token = 'AeO2UGaJ73+i/g1vvWaplrbKiO4dq+M1ASXDlXfHfNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}