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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cfa66d2d49700544fbbdec62658e0240d3c7e9e365e84f0254e0a5bce917496' 
  AND token = 'Q+tlxNyWbjcuCt5KX/o38QXA0tpgfF0MNEo+ssQ/GX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}