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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c35ed05547c19f108d5f9c457d26381d1bc5c0b3186703a28fcabdd1a8bfc570' 
  AND token = 'wSgli/W++81tv7iddb4f8v2ypz9Vch6Hs6PScczw+oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}