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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6aec84eec2f72cf81891a7f88cf6b2cb0eb09994926176494beb126eb6c2c4' 
  AND token = 'kV24g5gIsxMnFPeC2e59dDFFNc8zf7Rmhp3MkcuvW4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}