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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db83696640b9780b5e40cb4dcda1e84f273e4ee7941f246b1f44b9640668a826' 
  AND token = 'Cd7BcJ8cMSAsmxUsGo7gIki4+9bkXgOE2BqjMDYT4Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}