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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271529d593f2a4407bf17fb19632d9905f5b1dd41467e4acd30f0402adedcff4' 
  AND token = '9IxgUG73HhcH64qD/aTkIgGJar/lLf8xwXmdZL5PAds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}