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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7ce8d44fec870a79300b98a0c128e69b66d56fb9d92ab335ae516e8dced1bfa' 
  AND token = 'J3XlWNgtPVCSbIP4Vzppn3SIUVMaxD0G6nVYSkfJo7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}