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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1345d8cdab903ea765194fe89152d38cf10ac4ce0a88fe8ffde5293a0d2fd4' 
  AND token = 'ppai259RrEMh/V3Tutc3K54dzR2b2Kn+Iw3w31NXHv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}