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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9ff25e9c039c0e68ae8aa626545e5c9e244955b71c15a164efea039edfde68' 
  AND token = 'JqmVge6JP9FpigJqB4l1/HWk7VbA3s6oetdyyXk7s00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}