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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db0bf6f32de8bbb69b264e0b423f3d0a5889391d0d9327520fd2c70fe160319' 
  AND token = '+A0vyTSDuoHLOg1wKgCX+FNYxwfVympVeMLeA3es0jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}