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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd26743988bab8c7de1c36c5b961b515502eae07b74d7d34ebaf45417fe64d9' 
  AND token = 'cv+uSY3+ZOx7MYmw+e7jW545Ls046aP/F/mFgaif1pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}